Genotype profiles of Helicobacter pylori from gastric biopsies and strains with antimicrobial-induced resistance.

You-Hua WangFang-Fei WangXiao-Ling GongLi-Li YanQiao-Yun ZhaoYan-Ping SongRu-Lin ZhaoYa-Jing HeLinfu ZhouDong-Sheng LiuYong Xie

Published in: Therapeutic advances in gastroenterology (2020)

Genotype-based gastric biopsy analysis was reliable for determining clarithromycin and levofloxacin resistance. A2143G in 23S rRNA and N87K/D91N in the gyrA gene occurred in most resistant strains. Mutations in the rdxA gene were not good indicators of metronidazole resistance.

Keyphrases

helicobacter pylori
helicobacter pylori infection
copy number
staphylococcus aureus
diabetic rats
high glucose
genome wide identification
gene expression
dna methylation
oxidative stress
transcription factor
drug induced
stress induced