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Pathway-Based Mendelian Randomization for Pre-Infection IL-6 Levels Highlights Its Role in Coronavirus Disease.

Zoha KamaliNafiseh EsmaeilChris H L ThioAhmad VaezHarold Snieder
Published in: Genes (2024)
These potential causal relationships for pre-COVID-19 IL-6 levels with the risk of developing severe symptoms provide opportunities for further evaluation of these factors as prognostic/preventive markers of severe COVID-19. Further studies will need to clarify whether the higher risk for a severe disease course with lower baseline IL-6 levels may also extend to other infectious diseases.
Keyphrases
  • coronavirus disease
  • infectious diseases
  • sars cov
  • early onset
  • respiratory syndrome coronavirus
  • drug induced
  • climate change
  • risk assessment