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In silico analysis reveals mir-98-5p as a potential inhibitor of tumor cell proliferation and metastasis in colorectal cancer by targeting the fzd3 receptor of the Wnt signaling pathway.

Mutebi John KennethTushar Ahmed ShishirFahim Kabir Monjurul Haque
Published in: Journal, genetic engineering & biotechnology (2023)
The study reveals miR-98-5p as a novel target of FZD3 and an inhibitor of the Wnt signaling pathway hence being a potential candidate for developing targeted therapies against CRC.
Keyphrases
  • cell proliferation
  • signaling pathway
  • pi k akt
  • stem cells
  • epithelial mesenchymal transition
  • cell cycle
  • induced apoptosis
  • human health
  • molecular docking
  • binding protein
  • climate change