PKM2 enhances cancer invasion via ETS-1-dependent induction of matrix metalloproteinase in oral squamous cell carcinoma cells.

Young-Jin ParkJue Young KimDoo Young LeeXianglan ZhangShadavlonjid BazarsadWon-Yoon ChungJin Kim

Published in: PloS one (2019)

Collectively, this study unveiled the molecular mechanism underlying PKM2-mediated cancer invasion, thereby providing novel targets for therapeutics development against invasive OSCC.

Keyphrases

squamous cell
papillary thyroid
cell migration
squamous cell carcinoma
lymph node metastasis