Promoting Intratumoral Drug Accumulation by Bio-Membrane Regulated Active Targeting for Tumor Photothermal Therapy.
Chenkai YangXiangqian CaoLei HeCong WuMengxin ZhaoFei DuanZhiwen QiuXiaodong ZhuYilin YanShengzhou LiWei LiBing ShenPublished in: International journal of nanomedicine (2023)
In this study, we successfully developed a NIR-triggered nanomedicine that increased drug accumulation in tumor through photo-controlled therapy and homotypic targeting of the tumor cell membrane. GNR@TM has been demonstrated effective suppression of tumor growth, excellent biocompatibility, and significant potential for clinical applications.