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Knockdown of PTOV1 and PIN1 exhibit common phenotypic anti-cancer effects in MDA-MB-231 cells.

Shibendra Kumar Lal KarnaFaiz AhmadBilal Ahmad LoneYuba Raj Pokharel
Published in: PloS one (2019)
PTOV1 and PIN1 interact and exert oncogenic role in MDA-MB-231 cells by sharing the similar expression profile at transcriptional and translational level which can be a promising hub for therapeutic target.
Keyphrases
  • cell cycle arrest
  • induced apoptosis
  • cell death
  • breast cancer cells
  • gene expression
  • endoplasmic reticulum stress
  • healthcare
  • signaling pathway
  • network analysis
  • heat shock
  • bioinformatics analysis