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Cost per treatment responder analysis of atogepant compared to rimegepant for the preventive treatment of episodic migraine.

Jessica AilaniPranav GandhiAnjana LallaRashmi Halker SinghPeter McAllisterJonathan H SmithBrett DabruzzoNatty ChalermpalanupapKari KeltonStephanie J Nahas
Published in: Headache (2024)
Atogepant had substantially lower numbers needed to treat and costs per additional responder versus placebo than rimegepant for the preventive treatment of EM across all evaluated scenarios. These analyses suggest that atogepant may be more cost effective than rimegepant for the preventive treatment of EM. Limitations include differences in inclusion/exclusion criteria and in reporting of the ≥50% responder rates between trials.
Keyphrases
  • clinical trial
  • emergency department
  • combination therapy
  • replacement therapy
  • adverse drug