Metabolomic analysis of Shiga toxin 2a-induced injury in conditionally immortalized glomerular endothelial cells.

Christian PatryKathrin PlotnickiChristian BetzenAlba Perez OrtizKirk L PappanSimon C SatchellPeter W MathiesonMartina BielaszewskaHelge KarchBurkhard TönshoffNeysan Rafat

Published in: Metabolomics : Official journal of the Metabolomic Society (2019)

Stimulation of ciGEnC with TNFα + Stx2a is associated with profound metabolic changes indicative of increased inflammation, oxidative stress and energy turnover.

Keyphrases

high glucose
oxidative stress
endothelial cells
diabetic rats
escherichia coli
rheumatoid arthritis
dna damage
ischemia reperfusion injury
intellectual disability
bone mineral density
induced apoptosis
vascular endothelial growth factor
autism spectrum disorder
drug induced
body composition