Evidence for B cell maturation but not trained immunity in uninfected infants exposed to hepatitis C virus.
Anton LutckiiBenedikt StrunzAnton ZhirkovOlga FilipovichElena RukoiatkinaDenis GusevYuriy LobzinBjörn FischlerSoo AlemanMatti SällbergNiklas K BjörkströmPublished in: Gut (2020)
Our data reveal that exposure to, and infection with, HCV causes disparate effects on adaptive B cells and innate immune cell such as myeloid cells and NK cells in infants.
Keyphrases
- hepatitis c virus
- nk cells
- human immunodeficiency virus
- induced apoptosis
- immune response
- cell cycle arrest
- hiv infected
- bone marrow
- dendritic cells
- electronic health record
- genome wide
- acute myeloid leukemia
- big data
- endoplasmic reticulum stress
- single cell
- gene expression
- machine learning
- antiretroviral therapy
- data analysis