Design, Synthesis, and Pharmacological Evaluation of Novel Tacrine Derivatives as Multi-target ANTI-Alzheimer's Agents In Rat Models.
Remya R SRamalakshmi Natarajan Muralidharan PC N NaliniPublished in: Central nervous system agents in medicinal chemistry (2023)
The results showed that the novel Tacrine-Flavone hybrids are multitarget-directed ligands, which are safe and active compared to tacrine and can be a promising lead molecule for further study.