Aryl Pyrazoles from Photocatalytic Cycloadditions of Arenediazonium.
Luana CardinaleMichael NeumeierMichal MajekAxel Jacobi von WangelinPublished in: Organic letters (2020)
A photocatalytic synthesis of 1,5-diaryl pyrazoles from arenediazoniums and arylcyclopropanols is reported. The reaction proceeded under mild conditions (rt, 20 min) with catalytic [Ru(bpy)3]2+ under blue-light irradiation and exhibited compatibility with several functional groups (e.g., I, SF5, SO2NH2, N3, CN) and perfect levels of regiocontrol. Mechanistic studies (luminescence spectroscopy, CV, DFT, radical trapping, quantum yield determination) documented an initial oxidative quenching of the excited photocatalyst and the operation of a radical-chain mechanism.
Keyphrases
- energy transfer
- visible light
- highly efficient
- quantum dots
- reduced graphene oxide
- high resolution
- crystal structure
- single molecule
- density functional theory
- lymph node metastasis
- case control
- molecular docking
- molecularly imprinted
- solid phase extraction
- molecular dynamics
- mass spectrometry
- radiation induced
- perovskite solar cells