Host Biomarkers Reflect Prognosis in Patients Presenting With Moderate Coronavirus Disease 2019: A Prospective Cohort Study.

Arjun ChandnaRaman MahajanPriyanka GautamLazaro Mwandighanull nullPragya KumarGeorge M VargheseConstantinos KoshiarisYoel LubellSakib Burza

Published in: Open forum infectious diseases (2022)

Efficient resource allocation is essential for effective pandemic response. We measured host biomarkers in 420 patients presenting with moderate coronavirus disease 2019 and found that different biomarkers predict distinct clinical outcomes. Interleukin (IL)-1ra, IL-6, IL-10, and IL-8 exhibit dose-response relationships with subsequent disease progression and could potentially be useful for multiple use-cases.

Keyphrases

coronavirus disease
sars cov
high intensity
respiratory syndrome coronavirus
systemic lupus erythematosus
disease activity
ankylosing spondylitis