Conventional myelosuppressive chemotherapy for non-haematological malignancy disrupts the intestinal microbiome.
Lito E PapanicolasSarah K SimsSteven L TaylorSophie J MillerChristos S KarapetisSteve L WesselinghDavid L GordonGeraint B RogersPublished in: BMC cancer (2021)
Conventional chemotherapy results in significant changes in gut microbiota characteristics during the period of predicted myelosuppression post-chemotherapy. Further study is indicated to link microbiome changes during chemotherapy to clinical outcomes.