Effects of strontium ranelate on ligature-induced periodontitis in estrogen-deficient and estrogen-sufficient rats.
Letícia Macedo MarinsMarcelo Henrique NapimogaFernando de Souza MaltaTamires Szeremeske MirandaEdson Parra NaniBeatriz da Silva Tavares FrancoHélio Doyle Pereira da SilvaPoliana Mendes DuartePublished in: Journal of periodontal research (2019)
Strontium ranelate prevented ligature-induced BL in an estrogen-deficiency condition and, to a certain extent, increased TBA in the presence and absence of periodontal collapse in states of estrogen deficiency and estrogen sufficiency. Furthermore, strontium ranelate also affected the expression of bone markers, appearing to have acted predominantly as an anti-resorptive agent.