Lower birth weight is linked to poorer cardiovascular health in middle-aged population-based adults.
Zahra Raisi-EstabraghJackie CooperMae S BethellCeleste McCrackenAdam J LewandowskiPaul LeesonStefan NeubauerNicholas C HarveySteffen Erhard PetersenPublished in: Heart (British Cardiac Society) (2022)
Lower birth weight was associated with greater risk of incident MI and unhealthy LV phenotypes; effects were partially mediated through cardiometabolic disease and systemic inflammation. These findings support consideration of birth weight in risk prediction and highlight actionable areas for disease prevention.