Controlled human malaria infection (CHMI) outcomes in Kenyan adults is associated with prior history of malaria exposure and anti-schizont antibody response.

Melissa C KapuluDomtila KimaniPatricia NjugunaMainga HamalubaEdward OtienoRinter KimathiJames TujuB Kim Lee Simnull null

Published in: BMC infectious diseases (2022)

The CHMI model is highly effective in studying markers of naturally acquired immunity to malaria. Trial registration Clinicaltrials.gov number NCT02739763. Registered 15 April 2016.

Keyphrases

plasmodium falciparum
endothelial cells
clinical trial
phase iii
phase ii
metabolic syndrome
adipose tissue
insulin resistance
glycemic control
placebo controlled