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Long-Term Fasting-Induced Ketosis in 1610 Subjects: Metabolic Regulation and Safety.

Franziska GrundlerRobin MesnagePhillip M M RuppertDemetrios KouretasFrançoise Wilhelmi de Toledo
Published in: Nutrients (2024)
Our study showed that long-term fasting triggered ketosis, never reaching pathological levels, and that ketosis is influenced by age, gender, health, and the level of physical activity. Furthermore, it is modulated but not suppressed by minimal carbohydrate intake. Our study paves the way for better understanding how supplementation can modulate the therapeutic effects and tolerability of long-term fasting.
Keyphrases
  • physical activity
  • blood glucose
  • insulin resistance
  • mental health
  • adipose tissue
  • type diabetes
  • metabolic syndrome
  • skeletal muscle
  • blood pressure
  • oxidative stress
  • open label
  • diabetic rats
  • high glucose
  • double blind