Tripartite Motif-Containing 2, a Glutamine Metabolism-Associated Protein, Predicts Poor Patient Outcome in Triple-Negative Breast Cancer Treated with Chemotherapy.
Brendah K MasisiRokaya El AnsariLutfi AlfarsiAli FakrounBusra ErkanAsmaa IbrahimMichael TossIan O EllisEmad A RakhaAndrew R GreenPublished in: Cancers (2024)
This study provides evidence of an association between TRIM2 and poor patient outcomes in TNBC, especially those treated with chemotherapy. The molecular mechanisms and functional behaviour of TRIM2 and the functional link with GLS in BC warrant further exploration using in vitro models.