Association of daily physical activity with brain volumes and cervical spinal cord areas in multiple sclerosis.

Valerie J BlockShuiting ChengJeremy JuwonoRichard CuneoGina KirkishAmber M AlexanderMahir KhanAmit AkulaEduardo CaverzasiNico PapinuttoWilliam A SternMark J PletcherGregory M MarcusJeffrey E OlginStephen L HauserJeffrey M GelfandRiley M Bove Bruce Anthony Campbell CreeRoland G Henry

Published in: Multiple sclerosis (Houndmills, Basingstoke, England) (2022)

These results provide preliminary evidence that spinal cord GM area is a neuroanatomical substrate associated with STEPS. STEPS could serve as a proxy to alert clinicians and researchers to possible changes in structural nervous system pathology.

Keyphrases

spinal cord
physical activity
multiple sclerosis
white matter
neuropathic pain
spinal cord injury
resting state
palliative care
body mass index
functional connectivity
sleep quality
depressive symptoms
blood brain barrier
brain injury