A model-based assay design to reproduce in vivo patterns of acute drug-induced toxicity.

Lars KuepferOlivia ClaytonChristoph ThielHenrik CordesRamona NudischerLars M BlankVanessa BaierStephane HeymansFlorian CaimentAdrian RothDavid A FluriJens M KelmJosé CastellNathalie SelevsekRalph SchlapbachHector KeunJames HynesUgis SarkansHans GmuenderRalf HerwigSteven NiedererJohannes SchuchhardtMatthew SegallJos Kleinjans

Published in: Archives of toxicology (2017)

Keyphrases

drug induced
liver injury
high throughput
oxidative stress
adverse drug
intensive care unit
aortic dissection