Influence of timolol, benzalkonium-preserved timolol, and benzalkonium-preserved brimonidine on oxidative stress biomarkers in the tear film.
Lech SedlakWeronika WojnarMaria ZychDorota Wygledowska PromienskaPublished in: Cutaneous and ocular toxicology (2020)
This indicates that using BAC-preserved topical medications increases oxidative stress in the tear film and may, in the long-term, contribute to the clinical presentation of dry eye disease.