Association between low fetal fraction in cell-free DNA screening and fetal chromosomal aberrations: A systematic review and meta-analysis.
Ellis C BeckingEwoud SchuitSophie M E van Baar de KnegtErik A SistermansLidewij HennemanMireille N BekkerPeter G SchefferPublished in: Prenatal diagnosis (2023)
An LFF test result in cfDNA screening is associated with an increased risk of fetal trisomy 13, trisomy 18, monosomy X, and triploidy, but not trisomy 21. Further research is needed to assess the association between LFF and specific other types of fetal chromosomal aberrations. This article is protected by copyright. All rights reserved.
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