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Response to Comment on "Large-scale GWAS reveals insights into the genetic architecture of same-sex sexual behavior".

Andrea GannaKarin J H VerweijMichel G NivardRobert M MaierRobbee WedowAlexander Siegfried BuschAbdel AbdellaouiShengru GuoJ Fah Sathirapongsasutinull nullPaul LichtensteinSebastian LundströmNiklas LångströmAdam AutonKathleen Mullan HarrisGary W BeechamEden R MartinAlan R SandersJohn R B PerryBenjamin M NealeBrendan P Zietsch
Published in: Science (New York, N.Y.) (2021)
Hamer et al argue that the variable "ever versus never had a same-sex partner" does not capture the complexity of human sexuality. We agree and said so in our paper. But Hamer et al neglect to mention that we also reported follow-up analyses showing substantial overlap of the genetic influences on our main variable and on more nuanced measures of sexual behavior, attraction, and identity.
Keyphrases
  • genome wide
  • endothelial cells
  • mental health
  • copy number
  • induced pluripotent stem cells
  • gene expression
  • hepatitis c virus
  • hiv testing
  • hiv infected
  • genome wide association study