Exploring the sex difference in cardiovascular risk during growth hormone therapy in adults.

Tessa N A SlagboomAart Jan van der LelyMadeleine L DrentChrista C van Bunderen

Published in: European journal of endocrinology (2024)

Our results suggest that men with GHD did indeed experience more beneficial effects of GHRT on body composition and lipoprotein metabolism than women, at least in the early years of treatment. Also, the more unfavourable CV risk profile at baseline in men did not translate into a sex difference in the risk of developing CV and cerebrovascular morbidity during GHRT.

Keyphrases

body composition
growth hormone
resistance training
bone mineral density
middle aged
polycystic ovary syndrome
breast cancer risk
combination therapy
type diabetes
bone marrow
mesenchymal stem cells
pregnant women
cell therapy
high intensity