Tandem Dual-Site PbCu Electrocatalyst for High-Rate and Selective Glycine Synthesis at Industrial Current Densities.

Direct electrosynthesis of high-value amino acids from carbon and nitrogen monomers remains a challenge. Here, we design a tandem dual-site PbCu electrocatalyst for efficient amino acid electrosynthesis. Using oxalic acid (H 2 C 2 O 4 ) and hydroxylamine (NH 2 OH) as the raw reactants, for the first time, we have realized the flow-electrosynthesis of glycine at the industrial current density of 200 mA cm -2 with Faradaic efficiency over 78%. In situ ATR-FTIR spectroscopy characterizations reveal a favorable tandem pathway on the dual-site catalyst. Specifically, the Pb site drives the highly selective electroreduction of H 2 C 2 O 4 to form glyoxylic acid, and the Cu site accelerates the fast hydrogenation of oxime to form a glycine product. A glycine electrosynthesis (GES)-formaldehyde electrooxidation (FOR) assembly is further established, which synthesizes more valuable chemicals (HCOOH, H 2 ) while minimizing energy consumption. Altogether, we introduce a new strategy to enable the one-step electrosynthesis of high-value amino acid from widely accessible monomers.