High serum CRP influences myocardial miRNA profiles in ischemia-reperfusion injury of rat heart.

Eun Na KimChong Jai KimSo Ra KimJung-A SongHan ChoeKi-Bong KimJae-Sung ChoiSe Jin Oh

Published in: PloS one (2019)

We showed that when serum CRP level is high, IRI results in multiple miRNA profile changes not only in ischemic areas but also in non-ischemic myocardium. Our results may provide a strong basis for studying the role of CRP and miRNAs in ischemic heart disease.

Keyphrases

ischemia reperfusion injury
oxidative stress
heart failure
left ventricular
cerebral ischemia