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Population Pharmacokinetic Modelling of Ceftazidime and Avibactam in the Plasma and Epithelial Lining Fluid of Healthy Volunteers.

Richard DimelowJames G WrightMerran MacPhersonPaul NewellShampa Das
Published in: Drugs in R&D (2018)
This compartmental modelling analysis suggests ELF exposures of both ceftazidime and avibactam exceed levels required for efficacy in plasma.
Keyphrases
  • gram negative
  • multidrug resistant
  • klebsiella pneumoniae
  • air pollution
  • escherichia coli
  • data analysis