Clinical performance of a standardized SARS-CoV-2 interferon-γ release assay for simple detection of T-cell responses after infection or vaccination.
Marta Fernández-GonzálezVanesa AgullóSergio PadillaJosé Alberto GarcíaJavier García-AbellánÁngela BotellaPaula MascarellMontserrat Ruiz-GarcíaMar MasiáFélix GutiérrezPublished in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America (2021)
The IGRA assessed was a reliable method of quantifying T-cell response after SARS-COV-2 infection or vaccination. In convalescent patients the sensitivity is largely dependent on disease severity and time since primary infection. The assay is more likely to add clinical value to serology in patients with mild infections.