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Forsythoside B alleviates cerebral ischemia-reperfusion injury via inhibiting NLRP3 inflammasome mediated by SIRT1 activation.

Qiaoyu LiChongyang ZhangXiao SunMengchen WangZhixiu ZhangRongchang ChenXiaobo Sun
Published in: PloS one (2024)
FB demonstrated neuroprotective and anti-inflammatory effects by inhibiting the NLRP3 pathway through Sirt1 activation in CIRI.
Keyphrases
  • nlrp inflammasome
  • ischemia reperfusion injury
  • oxidative stress
  • signaling pathway
  • cerebral ischemia
  • subarachnoid hemorrhage
  • brain injury
  • cerebral blood flow