Outcomes following proton therapy for pediatric esthesioneuroblastoma.

Nicolette R DrescherDaniel J IndelicatoRoi DaganJulie A BradleyAdam L HoltzmanRaymond B Mailhot VegaPhilipp R AldanaEric S SandlerChristopher G MorrisWilliam M Mendenhall

Published in: Pediatric blood & cancer (2023)

A multimodality approach for pediatric EN results in excellent local control. Despite the moderate-dose PT, serious radiation toxicity was observed; further dose and target volume reductions may benefit select patients. Longer follow-up and comparative data from modern photon series are necessary to fully characterize any relative PT advantage.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
prognostic factors
oxidative stress
peritoneal dialysis
high intensity
radiation therapy
oxide nanoparticles