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Fabrication and desired properties of conductive hydrogel dressings for wound healing.

Lei NieQianqian WeiJingyu LiYaling DengXiaorui HeXinyue GaoXiao MaShuang LiuYanfang SunGuohua JiangOseweuba Valentine OkoroAbbey SymesShengli Jing
Published in: RSC advances (2023)
Conductive hydrogels are platforms recognized as constituting promising materials for tissue engineering applications. This is because such conductive hydrogels are characterized by the inherent conductivity properties while retaining favorable biocompatibility and mechanical properties. These conductive hydrogels can be particularly useful in enhancing wound healing since their favorable conductivity can promote the transport of essential ions for wound healing via the imposition of a so-called transepithelial potential. Other valuable properties of these conductive hydrogels, such as wound monitoring, stimuli-response etc. , are also discussed in this study. Crucially, the properties of conductive hydrogels, such as 3D printability and monitoring properties, suggest the possibility of its use as an alternative wound dressing to traditional dressings such as bandages. This review, therefore, seeks to comprehensively explore the functionality of conductive hydrogels in wound healing, types of conductive hydrogels and their preparation strategies and crucial properties of hydrogels. This review will also assess the limitations of conductive hydrogels and future perspectives, with an emphasis on the development trend for conductive hydrogel uses in wound dressing fabrication for subsequent clinical applications.
Keyphrases
  • tissue engineering
  • wound healing
  • reduced graphene oxide
  • drug delivery
  • hyaluronic acid
  • risk assessment
  • climate change
  • drug release
  • extracellular matrix
  • aqueous solution
  • tandem mass spectrometry