Age and sex specific thresholds for risk stratification of cardiovascular disease and clinical decision making: prospective open cohort study.
Zhe XuJuliet A Usher-SmithLisa PennellsRyan K ChungMatthew ArnoldLois KimStephen KaptogeMatthew SperrinEmanuele Di AngelantonioAngela M WoodPublished in: BMJ medicine (2024)
This study quantified the potential gains in cardiovascular disease-free life years when implementing prevention strategies based on age and sex specific risk thresholds instead of a fixed risk threshold for allocation of statin treatment. Such gains should be weighed against the costs of treating more younger people with statins for longer.