An advanced enrichment method for rare somatic retroelement insertions sequencing.

Alexander Y KomkovAnastasia A MinervinaGaiaz A NugmanovMariia V SaliutinaKonstantin V KhodosevichYuri B LebedevIlgar Z Mamedov

Published in: Mobile DNA (2018)

The developed technique can be used in combination with vast majority of modern RE identification approaches and can dramatically increase their capacity to detect rare somatic RE insertions in different types of cells.

Keyphrases

induced apoptosis
copy number
cell cycle arrest
single cell
endoplasmic reticulum stress
oxidative stress
cell death
bioinformatics analysis
cell proliferation
genome wide