Umbilical Cord Mesenchymal Stem Cell-Derived Small Extracellular Vesicles Deliver miR-21 to Promote Corneal Epithelial Wound Healing through PTEN/PI3K/Akt Pathway.

Xiaolong Liu Xuran Li Guangyuan Wu Pengfei QiYanyan ZhangZhiyu LiuXinyue LiYu YuXiangmei YeYang LiDongguang YangYueqiu TengCe ShiXin JinSen QiYuting LiuShudan WangYing LiuFenglin CaoQingran KongZhenkun Wang Hong Zhang

Published in: Stem cells international (2022)

HUMSC-sEVs could enhance the recovery of corneal epithelial wounds though restraining PTEN by transferring miR-21 and may represent a promising novel therapeutic agent for corneal wound repair.

Keyphrases

wound healing
umbilical cord
cell proliferation
mesenchymal stem cells
long non coding rna
pi k akt
long noncoding rna
bone marrow
stem cells
cell therapy