Coronary Artery Disease Risk Gene PRDM16 is Preferentially Expressed in Vascular Smooth Muscle Cells and a Potential Novel Regulator of Smooth Muscle Homeostasis.
Kunzhe DongXiangqin HeGuoqing HuYali YaoJiliang ZhouPublished in: bioRxiv : the preprint server for biology (2023)
is preferentially expressed in VSMCs and is a novel regulator of VSMC homeostasis. Future studies are warranted to investigate its role in VSMCs under pathological conditions such as atherosclerosis.
Keyphrases
- vascular smooth muscle cells
- smooth muscle
- coronary artery disease
- angiotensin ii
- transcription factor
- cardiovascular disease
- percutaneous coronary intervention
- coronary artery bypass grafting
- current status
- genome wide
- cardiovascular events
- genome wide identification
- heart failure
- human health
- type diabetes
- acute coronary syndrome
- genome wide analysis
- ejection fraction