FGF-induced LHX9 regulates the progression and metastasis of osteosarcoma via FRS2/TGF-β/β-catenin pathway.

Shuang-Qing LiChao TuLu WanRui-Qi ChenZhi-Xi DuanXiao-Lei RenZhi-Hong Li

Published in: Cell division (2019)

This study revealed LHX9 was essential for the proliferation, migration, invasion, and metastasis of OS cells via FGF and TGF-β/β-catenin signaling pathways.

Keyphrases

signaling pathway
induced apoptosis
transforming growth factor
epithelial mesenchymal transition
cell cycle arrest
pi k akt
cell proliferation
high glucose
diabetic rats
single cell
endoplasmic reticulum stress
cell death