Molecular identification and biofilm formation of aerobic and anaerobic coinfection bacterial isolated from cystic fibrosis patients in southwest Iran from 2014 to 2022.
Sasan MoogahiFateme Tadi BeniMohammad HashemzadehAram Asareh Zadegan DezfuliPublished in: Molecular biology reports (2023)
In conclusion, P. aeruginosa was found to be the most frequently isolated bacterium from patients with CF, and many of these bacteria could form biofilms. Additionally, the high prevalence of antibiotic resistance indicates the urgent need for increased attention to antibiotic preparation and patient screening concerning bacterial coinfections and the virulence and adhesion factors of these bacteria. Furthermore, the present study demonstrates that the coinfection of bacteria with high antibiotic resistance and a high capacity for biofilm formation can pose a life-threatening risk to CF patients, mainly due to their weakened immune systems.
Keyphrases
- biofilm formation
- pseudomonas aeruginosa
- cystic fibrosis
- candida albicans
- end stage renal disease
- staphylococcus aureus
- escherichia coli
- chronic kidney disease
- ejection fraction
- newly diagnosed
- peritoneal dialysis
- prognostic factors
- lung function
- working memory
- antimicrobial resistance
- air pollution
- patient reported
- wastewater treatment
- single molecule
- cell migration