Effects of sodium-glucose transporter-2 inhibition on systemic hemodynamics, renal function, and intra-renal oxygenation in sepsis-associated acute kidney injury.
Abraham H HulstConnie P C OwClive N MaySally H HoodMark P PlummerJeroen HermanidesDaniël H van RaalteAdam M DeaneRinaldo BellomoYugeesh R LankadevaPublished in: Intensive care medicine experimental (2024)
In a large mammalian model of septic AKI, a single dose of empagliflozin did not improve renal microcirculatory perfusion, oxygenation, kidney function, or histopathology.