High Serum Levels of Caspase-3 and Early Mortality in Patients with Severe Spontaneous Intracerebral Hemorrhage.

Leonardo LorenteMaría M MartínAntonia Pérez-CejasAgustín F González-RiveroRafael SabatelLuis RamosMónica ArguesoJordi Solé-ViolánJuan J CáceresAlejandro JiménezVictor García-Marín

Published in: Neurocritical care (2021)

The new findings of our study are that serum caspase-3 levels are associated with early mortality in patients with severe supratentorial SIH at different sites and that those levels during the first week of SIH are higher in non-survivors than in survivors.

Keyphrases

cell death
cardiovascular events
young adults
early onset
induced apoptosis
risk factors
brain injury
type diabetes
clinical trial
signaling pathway
placebo controlled