Nanomaterial-wrapped dsCYP15C1, a potential RNAi-based strategy for pest control against Chilo suppressalis.

A critical role for CsCYP15C1 function in molting is supported by sequence similarity with known juvenile hormone epoxidases, its expression profile, and abnormal molting phenotypes associated with RNA-mediated knockdown. CsCYP15C1 is thus a prime target for controlling C. suppressalis. Furthermore, RNAi-mediated characterization of candidate gene function can be enhanced by incorporating an enveloping nanomaterial. © 2020 Society of Chemical Industry.