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Soy isoflavones induces mitophagy to inhibit the progression of osteosarcoma by blocking the AKT/mTOR signaling pathway.

Ziang ZhengXinghan ZhaoBo YuanShan JiangRushan YanXiaowei DongQijun YaoHaidong Liang
Published in: Molecular medicine (Cambridge, Mass.) (2024)
SI induces mitophagy in OS cells by blocking the AKT/mTOR pathway, contributing to the inhibition of OS.
Keyphrases
  • signaling pathway
  • induced apoptosis
  • cell proliferation
  • pi k akt
  • cell cycle arrest
  • epithelial mesenchymal transition
  • nlrp inflammasome
  • endoplasmic reticulum stress
  • oxidative stress
  • cell death
  • room temperature