Cardiovascular Risk Factors in Children with Obesity, Preventive Diagnostics and Possible Interventions.
Mirjam MočnikNataša Marčun VardaPublished in: Metabolites (2021)
The increasing burden of obesity plays an essential role in increased cardiovascular morbidity and mortality. The effects of obesity on the cardiovascular system have also been demonstrated in childhood, where prevention is even more important. Obesity is associated with hormonal changes and vascular dysfunction, which eventually lead to hypertension, hyperinsulinemia, chronic kidney disease, dyslipidemia and cardiac dysfunction-all associated with increased cardiovascular risk, leading to potential cardiovascular events in early adulthood. Several preventive strategies are being implemented to reduce the cardiovascular burden in children. This paper presents a comprehensive review of obesity-associated cardiovascular morbidity with the preventive diagnostic workup at our hospital and possible interventions in children.
Keyphrases
- metabolic syndrome
- insulin resistance
- weight loss
- high fat diet induced
- cardiovascular events
- type diabetes
- cardiovascular risk factors
- weight gain
- chronic kidney disease
- cardiovascular disease
- physical activity
- coronary artery disease
- adipose tissue
- heart failure
- emergency department
- risk factors
- left ventricular
- depressive symptoms
- early life
- peritoneal dialysis
- drug induced