Neoadjuvant therapy does not impact the biliary microbiome in patients with pancreatic cancer.

Shay Behrens Thomas Lee Sutton Ranish K PatelIssac R SchwantesJack O'GradyAlicia JohnsonAaron GrossbergCharles LopezErin GilbertSkye MayoBrett C Sheppard

Published in: Journal of surgical oncology (2023)

Biliary stenting is the greatest predictor for positive biliary cultures and SSIs in resected PDAC patients. Neither NAC nor radiotherapy impact bile culture positivity, speciation, rates, or antibiotic resistance patterns, and perioperative antibiotic prophylaxis should not differ.

Keyphrases

lymph node
end stage renal disease
prognostic factors
newly diagnosed
locally advanced
ejection fraction
early stage
cardiac surgery
transcription factor
stem cells
patients undergoing
radiation therapy
mesenchymal stem cells
bone marrow
cell therapy
acute kidney injury