Antidepressant Effect of Sodium Butyrate is Accompanied by Brain Epigenetic Modulation in Rats Subjected to Early or Late Life Stress.

Samira Silva ValvassoriRoger Bitencourt VarelaWilson Rodrigues ResendeTaise Possamai-DellaLaura de Araujo BorbaJoão Paulo BehenckGislaine Zilli RéusJoão Quevedo

Published in: Current neurovascular research (2024)

These results suggest that epigenetics can play an important role in major depression pathophysiology triggered by early or late life stress and its treatment.

Keyphrases

major depressive disorder
gene expression
white matter
resting state
multiple sclerosis
functional connectivity
heat stress
combination therapy
replacement therapy
smoking cessation