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Docking, Synthesis, and Evaluation of 4-hydroxy-1-phenyl-2(1H)-quinolone Derivatives as Anticancer Agents.

Chaitali Prabhu TendulkarPrachita Gauns DessaiShivalingrao MamleDesaiAmrita Kadam
Published in: Current drug discovery technologies (2023)
Compound IVg showed the highest MolDock score and was also found to be most potent against both the cell line, A549, and MDA-MB.
Keyphrases
  • molecular dynamics
  • breast cancer cells
  • molecular dynamics simulations
  • protein protein
  • anti inflammatory
  • cell cycle arrest
  • small molecule
  • cell proliferation