Xylose induces cellulase production in Thermoascus aurantiacus.
Timo SchuergJan-Philip PrahlRaphael GabrielSimon HarthFirehiwot TacheaChyi-Shin ChenMatthew MillerFabrice MassonQian HeSarah BrownMona MirshiaghiLing LiangLauren M TomDeepti TanjoreNing SunTodd R PraySteven W SingerPublished in: Biotechnology for biofuels (2017)
Xylose induces both cellulase and xylanase production in T. aurantiacus and was used to produce enzymes at up to the 19 L bioreactor scale. The demonstration of induction by xylose-rich hydrolysate and saccharification of deacetylated, dilute acid-pretreated corn stover suggests a scenario to couple biomass pretreatment with onsite enzyme production in a biorefinery. This work further demonstrates the potential for T. aurantiacus as a thermophilic platform for cellulase development.