Advances in cerebral perfusion imaging techniques in acute ischemic stroke.
Hui FangGuangchen HeYingsheng ChengFuyou LiangYueqi ZhuPublished in: Journal of clinical ultrasound : JCU (2022)
The application of cerebral perfusion imaging has demonstrated significant assessment benefits and an ability to establish an appropriate triage of patients with acute ischemic stroke (AIS) and large artery occlusion (LAO) in the extended time window. Computed tomography perfusion (CTP) and magnetic resonance imaging (MRI) are routinely used to determine the ischemic core, as well as the tissue at risk, to aid in therapeutic decision-making. However, the time required to transport patients to imaging extends the door-to-reperfusion time. C-arm cone-beam CT (CBCT) is a novel tomography technology that combines 2D radiography and 3D CT imaging based on the digital subtraction angiography platform. In comparison with CT or MRI perfusion techniques, CBCT combined with catheterized angiogram or therapy can serve as a "one-stop-shop" for the diagnosis and treatment of AIS, and greatly reduce the door to reperfusion time. Here, we review the current evidence on the efficacy and theoretical basis of CBCT, as well as other perfusion techniques, with the purpose to assist clinicians to establish an effective and repaid workflow for patients with AIS and LAO in clinical practice.
Keyphrases
- contrast enhanced
- computed tomography
- magnetic resonance imaging
- image quality
- dual energy
- acute ischemic stroke
- magnetic resonance
- high resolution
- diffusion weighted imaging
- positron emission tomography
- emergency department
- cerebral ischemia
- clinical practice
- decision making
- acute myocardial infarction
- cone beam computed tomography
- cone beam
- heart failure
- subarachnoid hemorrhage
- high throughput
- photodynamic therapy
- optical coherence tomography
- oxidative stress
- fluorescence imaging
- mesenchymal stem cells
- end stage renal disease
- ejection fraction
- palliative care
- prognostic factors
- atrial fibrillation
- patient reported outcomes
- coronary artery disease
- left ventricular
- blood brain barrier
- brain injury