Bevacizumab is associated with delayed anastomotic leak after low anterior resection with preoperative radiotherapy for rectal cancer: a case report.
Erika MachidaYasuyuki MiyakuraJun TakahashiSawako TamakiHideki IshikawaFumi HasegawaRina KikugawaShingo TsujinakaAlan Kawarai LeforToshiki RikiyamaPublished in: Surgical case reports (2019)
This patient highlights a rare late adverse event at the anastomotic site associated with bevacizumab treatment and preoperative chemo-radiotherapy. Signs and symptoms suggesting anastomotic complications should be thoroughly evaluated during bevacizumab treatment, even long after surgical resection.