Limbic-Predominant Age-Related TDP-43 Encephalopathy: LATE-Breaking Updates in Clinicopathologic Features and Biomarkers.

Published in: Current neurology and neuroscience reports (2022)

F-fluorodeoxyglucose PET that are greater than expected relative to levels of local AD pathology. Efforts are being made to develop TDP-43-specific radiotracers, molecularly specific biofluid measures, and genomic predictors of TDP-43. LATE is a highly prevalent neurodegenerative disease distinct from previously characterized cognitive disorders.

Keyphrases

amyotrophic lateral sclerosis
positron emission tomography
pet ct
computed tomography
early onset
copy number
pet imaging