Effects of systemic inhibitors of acid-sensing ion channels 1 (ASIC1) against acute and chronic mechanical allodynia in a rodent model of migraine.

Clément VerkestEmilie PiquetSylvie DiochotMélodie DauvoisMichel Lanteri-MinetEric Lingueglia Anne Baron

Published in: British journal of pharmacology (2018)

These pharmacological data support the involvement of peripheral ASIC1-containing channels in migraine cutaneous allodynia as well as in its chronification. They highlight the therapeutic potential of ASIC1 inhibitors as both an acute and prophylactic treatment for migraine.

Keyphrases

liver failure
drug induced
respiratory failure
neuropathic pain
aortic dissection
hepatitis b virus
spinal cord
machine learning
replacement therapy
artificial intelligence